Conus Venom Peptide Pharmacology

2012/03/14 by Richard J. Lewis, Sébastien Dutertre, Irina Vetter +1 · 26 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Nicotinic Acetylcholine Receptors Study #Receptor Mechanisms and Signaling #Neuropeptides and Animal Physiology

paper · doi:10.1124/pr.111.005322

Citations

• Solution structure of χ‐conopeptide MrIA, a modulator of the human norepinephrine transporter

Cited by

• A single stable topological stereoisomer of a two disulfide conotoxin mimetic demonstrates full potency on the human norepinephrine transporter
• Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA. [europepmc]
• Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. [europepmc]
• Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics? [europepmc]
• The insecticidal potential of venom peptides. [europepmc]
• Protease inhibitors from marine venomous animals and their counterparts in terrestrial venomous animals. [europepmc]
• Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies. [europepmc]
• Conduits of life's spark: a perspective on ion channel research since the birth of neuron. [europepmc]
• Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails. [europepmc]
• Discovery, synthesis, and structure-activity relationships of conotoxins. [europepmc]
• Conotoxins targeting nicotinic acetylcholine receptors: an overview. [europepmc]
• Inhibition of A-type potassium current by the peptide toxin SNX-482. [europepmc]
• An evolutionary biochemist's perspective on promiscuity. [europepmc]
• Why do we study animal toxins? [europepmc]
• Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management? [europepmc]
• The hitchhiker's guide to the voltage-gated sodium channel galaxy. [europepmc]
• Venoms of Heteropteran Insects: A Treasure Trove of Diverse Pharmacological Toolkits. [europepmc]
• High-throughput identification of novel conotoxins from the Chinese tubular cone snail (Conus betulinus) by multi-transcriptome sequencing. [europepmc]
• In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds. [europepmc]
• Cone Snails: A Big Store of Conotoxins for Novel Drug Discovery. [europepmc]
• Venomics: A Mini-Review. [europepmc]
• Genetic Associations between Voltage-Gated Calcium Channels and Psychiatric Disorders. [europepmc]
• Animal toxins - Nature's evolutionary-refined toolkit for basic research and drug discovery. [europepmc]
• From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery. [europepmc]
• Structure-Function of Neuronal Nicotinic Acetylcholine Receptor Inhibitors Derived From Natural Toxins. [europepmc]
• Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels. [europepmc]