The transient receptor potential channel TRPA1: from gene to pathophysiology

2012/09/21 by Bernd Nilius, Giovanni Appendino, Grzegorz Owsianik · 28 citations
Neuroscience · Agricultural and Biological Sciences · Medicine · #Ion Channels and Receptors #Postharvest Quality and Shelf Life Management #Phytochemicals and Antioxidant Activities

paper · doi:10.1007/s00424-012-1158-z

Citations

• Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes

Cited by

• Bimodal voltage dependence of TRPA1: mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation
• TRPA1 and issues relating to animal model selection for extrapolating toxicity data to humans
• Infrared light detection by the haller’s organ of adult american dog ticks, Dermacentor variabilis (Ixodida: Ixodidae)
• New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms? [europepmc]
• TRP channels coordinate ion signalling in astroglia. [europepmc]
• TRPA1 and other TRP channels in migraine. [europepmc]
• Transient receptor potential channel ankyrin-1 is not a cold sensor for autonomic thermoregulation in rodents. [europepmc]
• TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis. [europepmc]
• Skin temperature: its role in thermoregulation. [europepmc]
• Redox and nitric oxide-mediated regulation of sensory neuron ion channel function. [europepmc]
• TRPs in taste and chemesthesis. [europepmc]
• Phosphoinositide regulation of TRP channels. [europepmc]
• Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression. [europepmc]
• From foe to friend: using animal toxins to investigate ion channel function. [europepmc]
• Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms? [europepmc]
• Species-specific temperature sensitivity of TRPA1. [europepmc]
• Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila. [europepmc]
• The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1. [europepmc]
• Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in primary human osteoarthritic chondrocytes. [europepmc]
• TRP Channels in Skin Biology and Pathophysiology. [europepmc]
• TRPA1 channels promote astrocytic Ca 2+ hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid-β peptide. [europepmc]
• Physiology of Astroglia. [europepmc]
• Transient Receptor Potential (TRP) Channels. [europepmc]
• Inhibition of TRPA1 Attenuates Doxorubicin-Induced Acute Cardiotoxicity by Suppressing Oxidative Stress, the Inflammatory Response, and Endoplasmic Reticulum Stress. [europepmc]
• TRPA1 Antagonists for Pain Relief. [europepmc]
• The emerging role of fibroblast-like synoviocytes-mediated synovitis in osteoarthritis: An update. [europepmc]
• TRPA1 as a therapeutic target for nociceptive pain. [europepmc]
• Essential Oils: Chemistry and Pharmacological Activities. [europepmc]