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High-order parallel-in-time method for the monodomain equation in cardiac electrophysiology

2024/05/30 by Giacomo Rosilho de Souza, de Souza, Giacomo Rosilho, Simone Pezzuto +3
Engineering · Physics and Astronomy · #65L04 #65L10 #65L20 #65Y05 #Advancements in Semiconductor Devices and Circuit Design #FOS: Mathematics #Numerical Analysis (math.NA) #Photonic and Optical Devices #Quantum and electron transport phenomena

paper · pdf · doi:10.48550/arxiv.2405.19994

openalex publication_date 2024/05/30 · openalex created_date 2024/06/01 · openalex updated_date 2026/07/30

Abstract

Simulation of the monodomain equation, crucial for modeling the heart's electrical activity, faces scalability limits when traditional numerical methods only parallelize in space. To optimize the use of large multi-processor computers by distributing the computational load more effectively, time parallelization is essential. We introduce a high-order parallel-in-time method addressing the substantial computational challenges posed by the stiff, multiscale, and nonlinear nature of cardiac dynamics. Our method combines the semi-implicit and exponential spectral deferred correction methods, yielding a hybrid method that is extended to parallel-in-time employing the PFASST framework. We thoroughly evaluate the stability, accuracy, and robustness of the proposed parallel-in-time method through extensive numerical experiments, using practical ionic models such as the ten-Tusscher-Panfilov. The results underscore the method's potential to significantly enhance real-time and high-fidelity simulations in biomedical research and clinical applications.

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