2025/05/01 · 1 voice
Medicine · #Biology #Cognitive science #Science, Research, and Medicine
paper · pdf · doi:10.1242/jcs.264065
published in Journal of Cell Science 138(9) (The Company of Biologists)
openalex publication_date 2025/05/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/09
ABSTRACT Samantha Lewis is an Assistant Professor of Cell Biology, Development and Physiology at the University of California (UC) Berkeley in the USA. Samantha earned her bachelor's degree at Oregon State University, where she was first introduced to the fascinating genetics of mitochondrial genomes in Dee Denver's lab. In 2013, she completed her PhD in Genetics at UC Riverside with Bradley Hyman, studying the molecular genetics of mitochondrial genome replication in Caenorhabditis elegans. As a postdoctoral fellow in Jodi Nunnari's lab at UC Davis, she expanded her expertise into cell biological research on the replication and maintenance of mitochondrial DNA (mtDNA) in mammalian cells. In 2020, Samantha started her independent lab at UC Berkeley, where she combines genetic, molecular and cell biology approaches to understand the complicated pathways regulating the flow of genetic information through mitochondrial networks, and how these processes are affected in metabolic or neurodegenerative diseases. For our Special Issue on Cell Biology of Mitochondria, we spoke with Samantha over Zoom about her career path, the challenges that come with working on the ‘neglected’ mitochondrial genome and today's exciting new frontiers in mitochondrial research.