Fungal symbiont transmitted by free-living mice promotes type 2 immunity

2024/11/27 by Yun Liao, Iris H. Gao, Takato Kusakabe +19 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Health Professions · #Gut microbiota and health #IL-33, ST2, and ILC Pathways #Pediatric health and respiratory diseases

paper · doi:10.1038/s41586-024-08213-2

Cited by

• Gut fungi are associated with human genetic variation and disease risk
• Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype

Discussions

• #WeekendRead #FungiPower! Liao Gao Iliev &co show @ Nature that the stomach of wild, not lab, mice is colonized by an immunosilent fungus! Mucus alterations via diet or antibiotics drive a Th2 -not Th [bsky, 52 points, 0 comments]