Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER

2024/11/15 by Sahar Attar, Valentino E. Browning, Mary Krebs +10 · 1 voice · 9 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Cell biology #Chemistry #Computational biology #DNA #Molecular Biology Techniques and Applications #Molecular biology #Nucleic acid #RNA modifications and cancer #Single-cell and spatial transcriptomics

paper · open access · doi:10.1038/s41592-024-02512-2

published in Nature Methods 22(1), 156-165 (Nature Portfolio)

openalex publication_date 2024/11/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06

Citations

• A Threshold Selection Method from Gray-Level Histograms

Cited by

• One probe fits all: a highly customizable modular RNA in situ hybridization platform expanding the application of SABER DNA probes
• One probe fits all: a highly customizable modular RNA in situ hybridization platform expanding the application of SABER DNA probes. [europepmc]
• DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci. [europepmc]

Discussions

• The pSABER paper is now online! pSABER is a new method for amplifying in situ hybridization signals This work was driven by Sahar Attar and co-led by Ram Akliesh ([at] podocytes on the other app) wi [bsky, 54 points, 5 comments]