Ovarian Hyperstimulation Syndrome Caused by Pituitary Gonadotroph Adenoma Secreting Follicle-Stimulating Hormone

2007/02/01 by Mohammadreza Ghayuri, James H. Liu, James Liu
Medicine · #Pituitary Gland Disorders and Treatments #Hormonal Regulation and Hypertension #Ovarian cancer diagnosis and treatment

paper · doi:10.1097/01.aog.0000247316.60573.4a

Abstract

In Brief BACKGROUND: We report a highly exceptional case in which a gonadotroph adenoma was diagnosed in a patient with normal follicle-stimulating hormone (FSH) levels. CASE: A 30-year-old woman with a gonadotroph adenoma presented with hyperstimulation syndrome and normal FSH levels. After treatment of her adenoma she had regular menstrual cycles and subsequently conceived. CONCLUSION: Ovarian hyperstimulation caused by a gonadotroph adenoma in a premenopausal woman with normal FSH levels is extremely rare. However, we propose that gonadotroph adenomas be considered in the differential diagnosis of patients who have this constellation of abnormalities. The rare gonadotroph adenomas of the pituitary can lead to ovarian hyperstimulation syndrome in both premenopausal and postmenopausal women, even with normal immunoreactive follicle-stimulating hormone levels.

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