The Key Role of Epigenetics in Human Disease Prevention and Mitigation

2018/04/04 by Andrew P. Feinberg · 1 voice · 9 citations
Biochemistry, Genetics and Molecular Biology · #Epigenetics and DNA Methylation #Genetics and Neurodevelopmental Disorders #RNA modifications and cancer

paper · doi:10.1056/nejmra1402513

openalex publication_date 2018/04/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Epigenetics is the regulation of gene expression through alterations in DNA or associated factors (other than the DNA sequence). These factors control the diverse manifestations of diseases. Insights into epigenetic modification may lead to new therapies for common diseases.

Citations

• Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)

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Discussions

• ➡️ Feinberg, A. P. (2018). The Key Role of Epigenetics in Human Disease Prevention and Mitigation. New England Journal of Medicine, 378(14), 1323–1334. DOI: doi.org/10.1056/nejm... [bsky, 1 points, 0 comments]

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