Triple-Negative Breast Cancer

2010/11/10 by William D. Foulkes, Ian E. Smith, Jorge S. Reis-Filho +1 · 14 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Breast Cancer Treatment Studies #Advanced Breast Cancer Therapies #HER2/EGFR in Cancer Research

paper · doi:10.1056/nejmra1001389

Abstract

Triple-negative breast cancer, so called because it lacks expression of the estrogen receptor, progesterone receptor, and HER2, is often, but not always, a basal-like breast cancer. This review focuses on its origin, molecular and clinical characteristics, and treatment.

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