2019/01/01 by Hanna Ludwig, Ludwig, Hanna, Aneta Krogulska +1
Medicine · Nursing · #Child Nutrition and Feeding Issues #Food Allergy and Anaphylaxis Research #Infant Nutrition and Health #Nutrition and Health Studies
paper · doi:10.34763/devperiodmed.20192301.6778
openalex publication_date 2020/12/31 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/01
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy with varying degrees of severity. The acute form of the disease is manifested by vomiting, lethargy and pallor, which usually appear within 7-4 hours after food ingestion, and can lead to shock. The most common trigger foods are: cow's milk, soy, rice and oats. Chronic FPIES is typical for infants fed with cow's milk or soy infant formula and is manifested by chronic vomiting, diarrhea and failure to thrive. In the vast majority of patients with FPIES, the analysis of the clinical history is sufficient to diagnose and identify trigger foods. If the history is unclear, use an ora/ food challenge to help confirm the diagnosis. Long-term management of patients with FPIES involves elimination of the trigger foods, monitoring for FPIES resolution and caregivers' education. The majority of children acquire food tolerance at the age of 3-5.