Hyperforin-Induced Activation of the Pregnane X Receptor Is Influenced by the Organic Anion-Transporting Polypeptide 2B1

2018/12/20 by Anima M. Schäfer, Olivier Potterat, Isabell Seibert +2
Medicine · Agricultural and Biological Sciences · Pharmacology, Toxicology and Pharmaceutics · #Drug Transport and Resistance Mechanisms #Natural Compound Pharmacology Studies #Pharmacogenetics and Drug Metabolism

paper · pdf · doi:10.1124/mol.118.114066

Citations

• Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer
• St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
• Transport Function and Transcriptional Regulation of a Liver-Enriched Human Organic Anion Transporting Polypeptide 2B1 Transcriptional Start Site Variant