Sodium 4-Phenylbutyrate Protects against Cerebral Ischemic Injury

2004/06/30 by Xin Qi, Toru Hosoi, Yasunobu Okuma +2 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Endoplasmic Reticulum Stress and Disease #RNA regulation and disease #Autophagy in Disease and Therapy

paper · doi:10.1124/mol.104.001339

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• Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome
• Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis