St. John’s Wort Formulations Induce Rat CYP3A23-3A1 Independent of Their Hyperforin Content

2023/10/20 by Anima M. Schäfer, Marta Rysz, Marta A. Rysz +8
Materials Science · Agricultural and Biological Sciences · #Phytochemistry and Bioactive Compounds #Phytochemistry and biological activities of Ficus species #Natural Compound Pharmacology Studies

paper · pdf · doi:10.1124/molpharm.123.000725

Citations

• Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer
• St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor