Lactate and lactylation in cardiovascular diseases: current progress and future perspectives

2024/06/21 by Wengen Zhu, Siyu Guo, Junyi Sun +2
Biochemistry, Genetics and Molecular Biology · Medicine · #Mitochondrial Function and Pathology #Cardiovascular Function and Risk Factors #Adipose Tissue and Metabolism

paper · doi:10.1016/j.metabol.2024.155957

Citations

• Failing mouse hearts utilize energy inefficiently and benefit from improved coupling of glycolysis and glucose oxidation
• Cardiac Energy Metabolism in Heart Failure
• GLUT-1/PKM2 loop dysregulation in patients with non-ST-segment elevation myocardial infarction promotes metainflammation
• Exercise-induced endothelial Mecp2 lactylation suppresses atherosclerosis via the Ereg/MAPK signalling pathway