Does telomere elongation in cloned organisms lead to a longer lifespan if cancer is considered ?

2004/08/30 by M. Masa, Marc Masa, S. Cebrat +5
Biochemistry, Genetics and Molecular Biology · Medicine · #FOS: Biological sciences #Genetics, Aging, and Longevity in Model Organisms #Populations and Evolution (q-bio.PE) #Telomeres, Telomerase, and Senescence #q-bio.PE

paper · pdf · doi:10.48550/arxiv.q-bio/0408026

8 pages including 4 figures

arxiv created 2004/08/30 · openalex publication_date 2004/08/30 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

... By additionally considering a two-mutation model for carcinogenesis and indefinite proliferation by the activation of telomerase, we demonstrate that the risk of dying doe to cancer can outweigh the positive effect of longer telomeres on the longevity.

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