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A perceptual hash function to store and retrieve large scale DNA sequences

2014/12/17 by Jocelyn de Goër de Hervé, Myoung-Ah Kang, De Herve, Jocelyn De Goer +5
Biochemistry, Genetics and Molecular Biology · Computer Science · #Cell Image Analysis Techniques #Computational Engineering #Digital Media Forensic Detection #FOS: Biological sciences #FOS: Computer and information sciences #Finance #Fractal and DNA sequence analysis #Genomics (q-bio.GN) #and Science (cs.CE)

paper · pdf · doi:10.48550/arxiv.1412.5517

openalex publication_date 2014/12/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

This paper proposes a novel approach for storing and retrieving massive DNA sequences.. The method is based on a perceptual hash function, commonly used to determine the similarity between digital images, that we adapted for DNA sequences. Perceptual hash function presented here is based on a Discrete Cosine Transform Sign Only (DCT-SO). Each nucleotide is encoded as a fixed gray level intensity pixel and the hash is calculated from its significant frequency characteristics. This results to a drastic data reduction between the sequence and the perceptual hash. Unlike cryptographic hash functions, perceptual hashes are not affected by "avalanche effect" and thus can be compared. The similarity distance between two hashes is estimated with the Hamming Distance, which is used to retrieve DNA sequences. Experiments that we conducted show that our approach is relevant for storing massive DNA sequences, and retrieving them.

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