Understanding Bacteriophage Therapy as a Density-dependent Kinetic Process

2001/01/01 by ROBERT J.H. PAYNE, Robert J. H. Payne, Vincent A. A. Jansen +1 · 27 citations
Environmental Science · Biochemistry, Genetics and Molecular Biology · #Bacteriophages and microbial interactions #Protein Structure and Dynamics #Vibrio bacteria research studies

paper · doi:10.1006/jtbi.2000.2198

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• Phage–antibiotic synergy restores β-lactam efficacy in MDR Klebsiella quasipneumoniae biofilms and suppresses resistance
• A tale of tails: Sialidase is key to success in a model of phage therapy against K1-capsulated Escherichia coli. [europepmc]
• What are the limitations on the wider therapeutic use of phage? [europepmc]
• The factors affecting effectiveness of treatment in phages therapy. [europepmc]
• Population dynamics of a Salmonella lytic phage and its host: implications of the host bacterial growth rate in modelling. [europepmc]
• The habits of highly effective phages: population dynamics as a framework for identifying therapeutic phages. [europepmc]
• Bacteriophage secondary infection. [europepmc]
• Phage fitness may help predict phage therapy efficacy. [europepmc]
• Phage therapy dosing: The problem(s) with multiplicity of infection (MOI). [europepmc]
• Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms. [europepmc]
• Microencapsulation with alginate/CaCO 3 : A strategy for improved phage therapy. [europepmc]
• Information Phage Therapy Research Should Report. [europepmc]
• Temperate phages as self-replicating weapons in bacterial competition. [europepmc]
• Development and Validation of a Microtiter Plate-Based Assay for Determination of Bacteriophage Host Range and Virulence. [europepmc]
• Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System. [europepmc]
• Phage "delay" towards enhancing bacterial escape from biofilms: a more comprehensive way of viewing resistance to bacteriophages. [europepmc]
• Phage-Antibiotic Combination Treatments: Antagonistic Impacts of Antibiotics on the Pharmacodynamics of Phage Therapy? [europepmc]
• Pharmacologically Aware Phage Therapy: Pharmacodynamic and Pharmacokinetic Obstacles to Phage Antibacterial Action in Animal and Human Bodies. [europepmc]
• Pharmacological limitations of phage therapy. [europepmc]
• Bacteriophage uptake by mammalian cell layers represents a potential sink that may impact phage therapy. [europepmc]
• Engineered Bacteriophage Therapeutics: Rationale, Challenges and Future. [europepmc]
• The Efficacy of Phage Therapy in a Murine Model of Pseudomonas aeruginosa Pneumonia and Sepsis. [europepmc]
• Nanotechnology Based Approaches in Phage Therapy: Overcoming the Pharmacological Barriers. [europepmc]
• Reassessment of Historical Clinical Trials Supports the Effectiveness of Phage Therapy. [europepmc]
• Bacteriophage Adsorption: Likelihood of Virion Encounter with Bacteria and Other Factors Affecting Rates. [europepmc]
• Phage Therapy-Challenges, Opportunities and Future Prospects. [europepmc]