2016/03/02 by Kyoohyun Kim, Jonghee Yoon, Kim, Kyoohyun +9
Engineering · Physics and Astronomy · #Biological Physics (physics.bio-ph) #Digital Holography and Microscopy #FOS: Physical sciences #Medical Physics (physics.med-ph) #Microfluidic and Bio-sensing Technologies #Optical Coherence Tomography Applications #Optics (physics.optics)
paper · pdf · doi:10.48550/arxiv.1603.00592
openalex publication_date 2016/03/02 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
Three-dimensional imaging of biological cells is crucial for the investigation of cell biology, provide valuable information to reveal the mechanisms behind pathophysiology of cells and tissues. Recent advances in optical diffraction tomography (ODT) have demonstrated the potential for the study of various cells with its unique advantages of quantitative and label-free imaging capability. To provide insight on this rapidly growing field of research and to discuss its applications in biology and medicine, we present the summary of the ODT principle and highlight recent studies utilizing ODT with the emphasis on the applications to the pathophysiology of cells.