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Current status of clinical trials for phage therapy

2024/09/25 by Chidiebere F. Uchechukwu, Adedayo Shonekan · 1 voice · 1 citation
Environmental Science · Immunology and Microbiology · Agricultural and Biological Sciences · #Bacteriophages and microbial interactions #Microbial infections and disease research #Plant Virus Research Studies

paper · doi:10.1099/jmm.0.001895

Abstract

Recently, bacteriophages have been considered alternatives to antibacterial treatments. Infectious diseases continue to plague the world because bacteria can adapt and develop defence mechanisms against antibiotics. The growing incidence of antibiotic-resistant bacterial infections necessitated the development of new techniques for treating bacterial infections worldwide. Clinical trials have shown efficiency against antibiotic-resistant bacteria. However, scientists in future clinical trials should scrutinize phage resistance implications, assess combination strategies with antimicrobial agents and address challenges in phage therapy delivery for effective implementation.

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