Roscovitine Inhibits CaV3.1 (T-Type) Channels by Preferentially Affecting Closed-State Inactivation

2011/11/17 by Viktor Yarotskyy, Keith S. Elmslie · 17 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemistry #Ion Channels and Receptors #Ion channel regulation and function #Molecular biology #Type (biology)

paper · pdf · doi:10.1124/jpet.111.187104

published in Journal of Pharmacology and Experimental Therapeutics 340(2), 463-472 (American Society for Pharmacology and Experimental Therapeutics)

openalex publication_date 2011/11/17 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/06

Citations

• Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5

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• A mutation in Ca V 2.1 linked to a severe neurodevelopmental disorder impairs channel gating. [europepmc]
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