Immunoreactivity for p‐170 glycoprotein in malignant mesothelioma and in non‐neoplastic mesothelium of the pleura using the murine monoclonal antibody JSB‐1

1992/05/01 by Marc Ramael, Jan Van Den Bossche, Jan Van den Bossche +8
Medicine · #Occupational and environmental lung diseases #Medical Imaging and Pathology Studies #Pancreatic and Hepatic Oncology Research

paper · doi:10.1002/path.1711670103

Abstract

The results of an immunohistochemical study of P-170 glycoprotein immunoreactivity in human non-neoplastic mesothelium (35 cases) and in malignant mesothelioma (33 cases) using the murine monoclonal antibody JSB-1 are reported. The majority of malignant mesothelioma cases exhibited cytoplasmic and membrane immunoreactivity in neoplastic cells. These findings are highly significant when compared with the absence of immunoreactivity in normal mesothelium.

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