Comprehensive analysis of auditory nerve fiber responses using fiber-specific modeling

2026/07/03 by Rebecca C. Felsheim, David J. Sly, David Sly +2
Medicine · Neuroscience · #Cochlear implant #Cochlear nerve #Ear Surgery and Otitis Media #Electrophysiology #Hearing Loss and Rehabilitation #Hearing, Cochlea, Tinnitus, Genetics #Nerve fiber #Refractory (planetary science) #Refractory period

paper · doi:10.1152/jn.00044.2026

openalex publication_date 2026/07/03 · openalex created_date 2026/07/04 · openalex updated_date 2026/08/06

Abstract

Quantitative descriptions of electrically evoked auditory nerve responses are essential for improving cochlear implants. Using fiber-specific modeling, this study extracts a comprehensive set of response measures from pulse-train recordings of 118 auditory nerve fibers. Comparing fibers from acutely and chronically deafened animals reveals differences, e.g., in refractory properties and response rate. An investigation into the relationship between the measures revealed a dependency of the rate on the refractory properties and additionally on the dynamic range.

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