+7/−10 chromosome copy-number alteration in the elderly: A cautionary tale from 2 cases

2026/06/18 by Ege Cubuk, Kenneth Aldape, Martha Quezado +9
Biochemistry, Genetics and Molecular Biology · Medicine · #Genomic variations and chromosomal abnormalities #Prenatal Screening and Diagnostics #Microtubule and mitosis dynamics

paper · doi:10.1093/jnen/nlag070

Citations

• Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma
• High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13