The Evolutionary History of Human Skin Pigmentation

2019/07/30 by Jorge Rocha · 56 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Nursing · #Biochemical Analysis and Sensing Techniques #Biology #Evolutionary biology #Gene #Genetic variation #Genetics #Human evolutionary genetics #Natural selection #Phylogenetics #Selection (genetic algorithm) #Skin Protection and Aging #Skin color #Trait #Variation (astronomy) #melanin and skin pigmentation

paper · doi:10.1007/s00239-019-09902-7

published in Journal of Molecular Evolution 88(1), 77-87 (Springer Science+Business Media)

openalex publication_date 2019/07/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• Signatures of Positive Selection in Genes Associated with Human Skin Pigmentation as Revealed from Analyses of Single Nucleotide Polymorphisms
• Genetic Variation at the MC1R Locus and the Time since Loss of Human Body Hair
• Vitamin D and the evolution of human depigmentation
• Human pigmentation variation: Evolution, genetic basis, and implications for public health
• Basis for the gain and subsequent dilution of epidermal pigmentation during human evolution: The barrier and metabolic conservation hypotheses revisited
• Shades of complexity: New perspectives on the evolution and genetic architecture of human skin

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• Evolution, Prehistory and Vitamin D. [europepmc]
• Unraveling the roles of vitamin D status and melanin during Covid‑19 (Review). [europepmc]
• The evolution of human skin pigmentation involved the interactions of genetic, environmental, and cultural variables. [europepmc]
• Association of pigmentation related-genes polymorphisms and geographic environmental variables in the Chinese population. [europepmc]
• Environmental and Nutritional Determinants of Macular Pigment in a Mexican Population. [europepmc]
• Role of Amine Neurotransmitters and Their Receptors in Skin Pigmentation: Therapeutic Implication. [europepmc]
• Quantitative Human Paleogenetics: What can Ancient DNA Tell us About Complex Trait Evolution? [europepmc]
• Skin pigmentation and vitamin D-folate interactions in vascular function: an update. [europepmc]
• Evolutionary adaptation highlights the interconnection of fatty acids, sunlight, inflammation and epithelial adhesion. [europepmc]
• Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways. [europepmc]
• Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort. [europepmc]
• The evolution of human skin pigmentation: A changing medley of vitamins, genetic variability, and UV radiation during human expansion. [europepmc]
• A genome-wide genetic screen uncovers determinants of human pigmentation. [europepmc]
• Skin pigmentation related variants in Mexican population and interaction effects on serum 25(OH)D concentration and vitamin D deficiency. [europepmc]
• Genetic insights into the peoples who shaped the American continent. [europepmc]