Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer

2025/10/19 by Ben Haines, Ben J. Haines, McKenzie Kreamer +12 · 1 citation
Pharmacology, Toxicology and Pharmaceutics · Medicine · #Chemical Reactions and Isotopes #Cancer Treatment and Pharmacology #Berberine and alkaloids research

paper · doi:10.1021/acs.jmedchem.5c02014

Abstract

for radiosensitization of murine EO771 mammary gland tumors and found to be as effective as papaverine with an improved safety profile.

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