Opa1 Overexpression Ameliorates the Phenotype of Two Mitochondrial Disease Mouse Models

2015/06/01 by Gabriele Civiletto, Tatiana Varanita, Raffaele Cerutti +7 · 213 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #ATP Synthase and ATPases Research #Biology #Cell biology #Clinical phenotype #Computational biology #Disease #Gene #Genetics #Medicine #Metabolism and Genetic Disorders #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrial disease #Mitochondrion #Pathology #Phenotype

paper · pdf · doi:10.1016/j.cmet.2015.04.016

published in Cell Metabolism 21(6), 845-854 (Elsevier BV)

crossref issued 2015/06/01 · crossref published 2015/06/01 · crossref published-print 2015/06/01 · openalex publication_date 2015/06/01 · crossref created 2015/06/02 · crossref deposited 2018/09/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29 · crossref indexed 2026/07/29

Citations

• The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage
• Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
• Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
• OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

Cited by

• The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage
• Luca Scorrano [wikipedia]