2021/01/20 by Wenwen Ou, Zhijun Li, Qi Zheng +4 · 41 citations
Psychology · Medicine · #Obsessive-Compulsive Spectrum Disorders #Child Abuse and Trauma #Child and Adolescent Psychosocial and Emotional Development #Meta-analysis #Medicine #Sexual abuse #Confidence interval #Depressive symptoms #Cochrane Library #Obsessive compulsive #Childhood abuse #Psychiatry #Clinical psychology #Internal medicine #Poison control #Injury prevention #Anxiety
paper · pdf · doi:10.3389/fpsyt.2020.612586
published in Frontiers in Psychiatry 11, 612586 (Frontiers Media)
openalex publication_date 2021/01/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
Background: Previous studies have indicated that childhood maltreatment (CM) may potentially influence the clinical symptomatology of obsessive-compulsive disorder (OCD). Here, we aimed to quantify the relationship between CM and obsessive-compulsive symptoms (OCS) and depressive symptoms in OCD through a meta-analysis. Method: We searched PubMed, Embase, Cochrane Library, and PsycARTICLES databases for articles reporting the association between CM and OCD on April 15, 2020. Random-effect models were used to quantify the relationship between CM and the severity of OCS and depressive symptoms in OCD. Results: Ten records with 1,611 OCD patients were included in the meta-analysis. The results revealed that CM is positively correlated with the severity of OCS [ r = 0.10, 95%Confidence Interval (CI): 0.01–0.19, P = 0.04] as well as depressive symptoms in OCD ( r = 0.15, 95%CI: 0.07–0.24, P = 0.0002). For the subtypes of CM, childhood emotional abuse (CEA) and childhood sexual abuse (CSA) was related with the severity of OCS ( r = 0.11, 95%CI: 0.03–0.19, P = 0.009) and obsession ( r = 0.13, 95%CI: 0.03–0.23, P = 0.01), respectively. Conclusion: Our meta-analysis indicates that OCD patients who suffered more CM may exhibit more severe OCS and depressive symptoms.