A novel gain-of-function mutation in sgk-1 partially suppresses mTORC2 defects

2024/02/20 by David Cully, Natalie R. Cohen, Peter C. Breen +2
Biochemistry, Genetics and Molecular Biology · #Advanced Fluorescence Microscopy Techniques

paper · doi:10.17912/micropub.biology.001163

openalex publication_date 2024/02/20 · openalex created_date 2024/10/17 · openalex updated_date 2026/08/01

Abstract

This allele will be useful in further dissecting the mTORC2 pathway and provides new insight into the role of this conserved residue in regulating SGK-1 kinase activity.

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