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Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification

2013/12/08 by Housheng Hansen He, Clifford A. Meyer, Clifford A Meyer +14 · 212 citations
Biochemistry, Genetics and Molecular Biology · #Base sequence #Biology #Cleavage (geology) #Computational biology #DNA #DNA binding site #DNA footprinting #DNA-binding protein #DNase I hypersensitive site #Deoxyribonuclease I #Gene #Gene expression #Genetics #Genomics and Chromatin Dynamics #Hypersensitive site #Promoter #RNA Research and Splicing #RNA and protein synthesis mechanisms #Transcription (linguistics) #Transcription factor

paper · open access · doi:10.1038/nmeth.2762

published in Nature Methods 11(1), 73-78 (Springer Science and Business Media LLC)

crossref issued 2013/12/08 · crossref published 2013/12/08 · crossref published-online 2013/12/08 · openalex publication_date 2013/12/08 · crossref created 2013/12/08 · crossref published-print 2014/01/01 · openalex created_date 2016/06/24 · crossref deposited 2023/05/18 · crossref indexed 2026/07/08 · openalex updated_date 2026/08/01

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