Substitutions in woolly mammoth hemoglobin confer biochemical properties adaptive for cold tolerance

2010/05/02 by Kevin L Campbell, Kevin L. Campbell, Jason E E Roberts +19 · 90 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Adaptation (eye) #Biochemistry #Biology #Evolutionary biology #Gene #Genetics #Globin #Gut microbiota and health #Heme #Hemoglobin #Hemoglobin structure and function #Lineage (genetic) #Natural selection #Neuroscience of respiration and sleep #Phenotype #Selection (genetic algorithm)

paper · doi:10.1038/ng.574

published in Nature Genetics 42(6), 536-540 (Springer Science and Business Media LLC)

crossref issued 2010/05/02 · crossref published 2010/05/02 · crossref published-online 2010/05/02 · openalex publication_date 2010/05/02 · crossref created 2010/05/02 · crossref published-print 2010/06/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · crossref indexed 2026/06/30 · openalex updated_date 2026/08/01

Citations

• Novel high-resolution characterization of ancient DNA reveals C > U-type base modification events as the sole cause of post mortem miscoding lesions
• Sebaceous Glands of the Woolly Mammoth, Mammothus primigenius Blum.: Histological Evidence
• The pattern and process of mammoth evolution in Eurasia

Cited by

• Proteomic Analysis of a Pleistocene Mammoth Femur Reveals More than One Hundred Ancient Bone Proteins
• Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging
• Woolly mammoth [wikipedia]