2009/07/01 by Jerome Emeka Azike · 41 citations
Medicine · #Nonmelanoma Skin Cancer Studies #Cancer and Skin Lesions #Chemotherapy-related skin toxicity #Medicine #Scrotum #Basal cell #Disease #Epidemiology #Dispensary #Dermatology #General surgery #Surgery #Pathology
paper · pdf · doi:10.4081/rt.2009.e17
published in Rare Tumors 1(1), 47-49 (SAGE Publishing)
openalex publication_date 2009/07/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
Squamous cell carcinoma of the scrotum is a tumor that is of interest for clinical and historical reasons. It was the first cancer linked to occupational exposure when, in 1775, Perivall Pott described it in chimney sweeps in England. Other occupations that had a preponderance of the disease included people who worked with the distillates of coal and men exposed to mineral oil. Currently, the disease is very rare and most cases are thought to result from poor hygiene and chronic irritation. Surgery with a negative resection margin offers the best hope of cure as adjunctive therapy has not proved useful. Prognosis correlates with the extent of nodal involvement.