2012/06/26 by Adam MacNeil, Pierre E. Rollin · 89 citations
Medicine · Health Professions · #Viral Infections and Outbreaks Research #Viral Infections and Vectors #Disaster Response and Management #Neglected tropical diseases #Outbreak #Tropical disease #Marburg virus #Viral hemorrhagic fever #Ebola virus #Disease #Disease control #Virology #Ebolavirus #Rift Valley fever #Medicine #Pathology
paper · pdf · doi:10.1371/journal.pntd.0001546
published in PLoS neglected tropical diseases 6(6), e1546 (Public Library of Science)
openalex publication_date 2012/06/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06
Ebola hemorrhagic fever (EHF) and Marburg hemorrhagic fever (MHF) are rare viral diseases, endemic to central Africa. The overall burden of EHF and MHF is small in comparison to the more common protozoan, helminth, and bacterial diseases typically referred to as neglected tropical diseases (NTDs). However, EHF and MHF outbreaks typically occur in resource-limited settings, and many aspects of these outbreaks are a direct consequence of impoverished conditions. We will discuss aspects of EHF and MHF disease, in comparison to the "classic" NTDs, and examine potential ways forward in the prevention and control of EHF and MHF in sub-Saharan Africa, as well as examine the potential for application of novel vaccines or antiviral drugs for prevention or control of EHF and MHF among populations at highest risk for disease.