Chronic mild stress-induced anhedonia: A realistic animal model of depression

1992/01/01 by Paul Willner, Richard Muscat, Mariusz Papp · 964 citations
Medicine · Neuroscience · Psychology · #Anhedonia #Animal model #Animal models of depression #Animal studies #Antidepressant #Chronic stress #Depression (economics) #Dopamine #Hippocampus #Internal medicine #Medicine #Neuroscience #Neurotransmitter Receptor Influence on Behavior #Nucleus accumbens #Psychology #Stress Responses and Cortisol #Stressor #Tryptophan and brain disorders

paper · doi:10.1016/s0149-7634(05)80194-0

published in Neuroscience & Biobehavioral Reviews 16(4), 525-534 (Elsevier BV)

crossref issued 1992/01/01 · crossref published 1992/01/01 · crossref published-print 1992/01/01 · openalex publication_date 1992/01/01 · crossref created 2005/12/15 · crossref deposited 2023/05/05 · openalex created_date 2025/10/10 · crossref indexed 2026/08/07 · openalex updated_date 2026/08/08

Citations

• Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
• Comparison of two modes of stress measurement: Daily hassles and uplifts versus major life events
• Neuroleptics and operant behavior: The anhedonia hypothesis

Cited by

• Intracranial self-stimulation and sucrose intake differ as hedonic measures following chronic mild stress: interstrain and interindividual differences
• Chronic Mild Stress (CMS) Revisited: Consistency and Behavioural-Neurobiological Concordance in the Effects of CMS
• Animal models of mood disorders: recent developments
• Animal models of depression [wikipedia]