2009/11/12 by Svetlana Dragojević-Dikić, S. Rakic, Branka Nikolić +1 · 35 citations
Medicine · #Ovarian function and disorders #Reproductive Biology and Fertility #Assisted Reproductive Technology and Twin Pregnancy #Premature ovarian failure #Premature Menopause #Premature ovarian insufficiency #Medicine #Pregnancy #Menopause #Premature birth #Hormone replacement therapy (female-to-male) #Gynecology #Obstetrics #Gestation #Endocrinology #Internal medicine
paper · doi:10.3109/09513590903004126
published in Gynecological Endocrinology 25(12), 769-772 (Informa)
openalex publication_date 2009/11/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22
Premature ovarian failure (POF), premature ovarian insufficiency, premature menopause or hypergonadotropic hypogonadism, a serious life-changing condition that affects young women, remains an enigma and the researcher's challenge. In the present article we described a case of singleton pregnancy in a 33-year-old patient, presenting with POF and treated with hormone replacement therapy. Twenty months later this therapy led to maturation of one follicle, recruitment and fertilisation of the residual oocyte and spontaneous pregnancy ensued. A normal infant was delivered by cesarean section.