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Do E‐cigarettes induce weight changes and increase cardiometabolic risk? A signal for the future

2017/06/29 by Ann Verhaegen, L. Van Gaal · 1 citation
Medicine · #Adipokines, Inflammation, and Metabolic Diseases #Adipose Tissue and Metabolism #Cardiovascular Disease and Adiposity #Environmental health #Gerontology #Medicine

paper · doi:10.1111/obr.12568

openalex publication_date 2017/06/29 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15

Abstract

The prevalence of non-cigarette tobacco use in electronic cigarettes, also called vaping, is rapidly increasing, especially in adolescents and young adults, due to attractive marketing techniques promoting them as healthier alternatives to conventional tobacco cigarettes. Although smoking is associated with weight loss, it increases insulin resistance and attributes to other features of the metabolic syndrome, increasing the cardiometabolic risk profile. Whether vaping has the same deleterious effects on metabolic parameters as regular cigarette smoke has not yet been studied thoroughly in humans. However, animal model experiments attribute comparable effects of e-cigarette smoking, even without nicotine exposure, on weight and metabolic parameters as compared to smoking cigarettes. In this review paper, we want to give an overview of published data on the effects on weight and cardiometabolic parameters of e-cigarette use and formulate some mechanistic hypotheses.

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