A withdrawal syndrome after abrupt discontinuation of alprazolam

1985/01/01 by R Noyes, John Clancy, William Coryell +3 · 48 citations
Medicine · Neuroscience · #Alprazolam #Anesthesia #Anesthesia and Sedative Agents #Anxiety #Discontinuation #Drug #Drug withdrawal #Epilepsy research and treatment #Medicine #Neuroscience and Neuropharmacology Research #Psychiatry #Withdrawal syndrome

paper · doi:10.1176/ajp.142.1.114

published in American Journal of Psychiatry 142(1), 114-116 (American Psychiatric Association)

openalex publication_date 1985/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11

Abstract

A patient who received therapeutic doses of alprazolam for 8 weeks experienced a withdrawal syndrome beginning 18 hours after its abrupt discontinuation. Short-acting and minimally sedating benzodiazepines may have increased potential for withdrawal reactions.

Citations

• Withdrawal Phenomena after Long-term Administration of Benzodiazepines A Review of Recent Investigations

Cited by

• Benzodiazepine withdrawal syndrome [wikipedia]