Evolution of Drug Resistance in Mycobacterium tuberculosis : Clinical and Molecular Perspective

2002/02/01 by Stephen H. Gillespie · 1 citation
Medicine · #Tuberculosis Research and Epidemiology #Mycobacterium research and diagnosis #Diagnosis and treatment of tuberculosis #Chemotherapy #Mycobacterium tuberculosis #Tuberculosis #Drug resistance #Medicine #Antimicrobial chemotherapy #Drug #Perspective (graphical) #Multiple drug resistance #Virology #Microbiology #Antibiotics #Biology #Pharmacology #Pathology #Surgery

paper · doi:10.1128/aac.46.2.267-274.2002

openalex publication_date 2002/02/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/22

Abstract

The story of antituberculosis chemotherapy is a miniature of the history of anti-infective chemotherapy. In the first half of the 20th century the problem of tuberculosis appeared insoluble: the lipid-rich cell wall was believed to make chemotherapy impossible ([21][1]). This gloomy view seemed to

Citations

• An Outbreak of Multidrug-Resistant Tuberculosis among Hospitalized Patients with the Acquired Immunodeficiency Syndrome
• Molecular genetic basis of antimicrobial agent resistance inMycobacterium tuberculosis: 1998 update
• Ebonics, Standard English, and Teacher Expectations.
• MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

Cited by

• Multidrug-resistant tuberculosis [wikipedia]