2025/10/03 by Marianne Cloeren, John Dement, Jane Quackenbush +2
paper · doi:10.1002/ajim.70026
crossref issued 2025/10/03 · crossref published 2025/10/03 · crossref published-online 2025/10/03 · crossref created 2025/10/03 · crossref published-print 2025/11/01 · crossref deposited 2026/02/17 · crossref indexed 2026/08/06
ABSTRACT Background Age‐related hearing loss is associated with increased dementia risk. We examined the association between hearing loss and dementia in a population at high risk for hearing loss from occupational noise exposures. Methods We conducted cross‐sectional and longitudinal analyses using logistic regression and interval‐censored Cox models using data from the Building Trades National Medical Screening Program (BTMed), from inception in 1996 through March 2024. Hearing loss was defined as a speech‐frequency pure‐tone average ≥ 20 decibels (dB) in the better ear and categorized as mild (20–34 dB), moderate (35–49 dB), moderately severe (50–64 dB), or severe to complete (≥ 65 dB). Dementia was defined using criteria from medical history, physical exams, and medication data across all medical screening examinations. Results The study included 44,000 exams in 24,958 BTMed participants; 54.6% had hearing loss. Hearing loss was strongly associated with dementia prevalence (211 cases, p p ‐trend = 0.0928) for incident dementia. Discussion Cross‐sectional results support an association between occupational hearing loss and dementia, consistent in direction with findings for age‐related hearing loss; longitudinal estimates were not significant but were directionally similar. If confirmed in other high‐risk cohorts with repeated audiometry, these findings underscore the potential for hearing conservation and hearing loss rehabilitation in dementia prevention.