The Emerging Role of IL-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings

2012/06/07 by David A. Martin, Jennifer E. Towne, Gregory Kricorian +5 · 27 citations
Immunology and Microbiology · Medicine · #Psoriasis: Treatment and Pathogenesis #Dermatology and Skin Diseases #Asthma and respiratory diseases

paper · doi:10.1038/jid.2012.194

Citations

• Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
• Attributable Risk Estimate of Severe Psoriasis on Major Cardiovascular Events

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• Aquaporin-3-mediated hydrogen peroxide transport is required for NF-κB signalling in keratinocytes and development of psoriasis. [europepmc]
• Increased expression of interleukin-17 pathway genes in nonlesional skin of moderate-to-severe psoriasis vulgaris. [europepmc]
• Low-Dose IL-17 Therapy Prevents and Reverses Diabetic Nephropathy, Metabolic Syndrome, and Associated Organ Fibrosis. [europepmc]
• The role of IL-17 in vitiligo: A review. [europepmc]
• Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques. [europepmc]
• An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis. [europepmc]
• Old and New Biological Therapies for Psoriasis. [europepmc]
• Scanning the Immunopathogenesis of Psoriasis. [europepmc]
• Underdiagnosed and undertreated psoriasis: Nuances of treating psoriasis affecting the scalp, face, intertriginous areas, genitals, hands, feet, and nails. [europepmc]
• Ichthyosis molecular fingerprinting shows profound T H 17 skewing and a unique barrier genomic signature. [europepmc]
• Human αβ and γδ T Cells in Skin Immunity and Disease. [europepmc]
• The Immunologic Role of IL-17 in Psoriasis and Psoriatic Arthritis Pathogenesis. [europepmc]
• The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond. [europepmc]
• IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients. [europepmc]
• Interleukin-17A and Keratinocytes in Psoriasis. [europepmc]
• Immunity to commensal skin fungi promotes psoriasiform skin inflammation. [europepmc]
• Phage Display Derived Monoclonal Antibodies: From Bench to Bedside. [europepmc]
• Much More Than IL-17A: Cytokines of the IL-17 Family Between Microbiota and Cancer. [europepmc]
• Interleukin-17 and Interleukin-23: A Narrative Review of Mechanisms of Action in Psoriasis and Associated Comorbidities. [europepmc]
• Signaling pathways and targeted therapies for psoriasis. [europepmc]