vix.ing · top · new · best · stats · spec

Analysis of Y-chromosomal short tandem repeat (STR) polymorphism in an Iranian Sadat population

2009/08/01 by Mahmoud‐Reza Rafiee, A. Sokhansanj, Maryam Naghizadeh +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Biology #Genetics #Human genetics #Tandem repeat #Polymorphism (computer science) #Chromosomal polymorphism #Genotype #Gene #Genome #Chromosome #Karyotype

paper · doi:10.1134/s1022795409080110

openalex publication_date 2009/08/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/19

Abstract

The molecular genotyping of individuals and reconstruction of kinship through short and highly polymorphic DNA markers, so called short tandem repeats (STR), has become one of the important and efficient methods in anthropology studies and forensic science. Although many populations have been analyzed, no study has yet been carried out on Sadat populations who are putative descendents of Prophet Mohammad (peace be upon him). Polymorphisms of 6 Y-STR loci (DYS19, DYS385a/b, DYS389II, DYS390, DYS392, and DYS393) have been studied in an unrelated population of Sadat males. The aim of this study was to find possible similarities within Sadat males, resided in Iran. Among Sadat, DYS385b was proved to be the most polymorphic (GD = 0.8588), and DYS392 showed the lowest polymorphism (GD = 0.3527). In 50 samples, 45 different haplotypes were found, of which 39 haplotypes were unique. In the study, three samples had multi-allelic patterns. Haplotype diversity, in regard to these 7 markers was 0.9942.

Cited by