Genetic make up and structure of Colombian populations by means of uniparental and biparental DNA markers

2010/06/08 by Winston Rojas, María Victoria Parra, Omer Campo +16 · 4 citations
Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genetic diversity and population structure #Race, Genetics, and Society #Biology #Mitochondrial DNA #Population #Genetic diversity #Y chromosome #Evolutionary biology #Genetic admixture #Genetics #Chromosome #Genetic marker #Geography #Demography #Gene

paper · doi:10.1002/ajpa.21270

openalex publication_date 2010/06/08 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/23

Abstract

Colombia is a country with great geographic heterogeneity and marked regional differences in pre-Columbian native population density and in the extent of past African and European immigration. As a result, Colombia has one of the most diverse populations in Latin America. Here we evaluated ancestry in over 1,700 individuals from 24 Colombian populations using biparental (autosomal and X-Chromosome), maternal (mtDNA), and paternal (Y-chromosome) markers. Autosomal ancestry varies markedly both within and between regions, confirming the great genetic diversity of the Colombian population. The X-chromosome, mtDNA, and Y-chromosome data indicate that there is a pattern across regions indicative of admixture involving predominantly Native American women and European and African men.

Citations

• Skin pigmentation, biogeographical ancestry and admixture mapping
• Genetic Variation and Population Structure in Native Americans
• Admixture dynamics in Hispanics: A shift in the nuclear genetic ancestry of a South American population isolate
• Geographic Patterns of Genome Admixture in Latin American Mestizos
• A Genomewide Admixture Map for Latino Populations
• The Emerging Tree of West Eurasian mtDNAs: A Synthesis of Control-Region Sequences and RFLPs
• Y chromosomal haplogroup J as a signature of the post-neolithic colonization of Europe
• New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree
• Reduced genetic structure of the Iberian peninsula revealed by Y-chromosome analysis: implications for population demography
• Strong Amerind/White Sex Bias and a Possible Sephardic Contribution among the Founders of a Population in Northwest Colombia

Cited by

• Admixture and Genetic Diversity Distribution Patterns of Non-Recombining Lineages of Native American Ancestry in Colombian Populations
• Coancestría de apellidos y linajes del cromosoma Y en el noroeste de Colombia: una herramienta útil para establecer migración entre poblaciones
• Colombia’s racial crucible: Y chromosome evidence from six admixed communities in the Department of Bolivar
• Haplogroup T-M184 [wikipedia]