2002/12/17 by Edward Kim · 146 citations
Medicine · Psychology · #Traumatic Brain Injury Research #Psychosomatic Disorders and Their Treatments #Attention Deficit Hyperactivity Disorder #Disinhibition #Aggression #Traumatic brain injury #Psychology #Neuropsychology #Clinical psychology #Poison control #Psychiatry #Medicine #Cognition #Medical emergency
paper · doi:10.3233/nre-2002-17404
published in Neurorehabilitation 17(4), 297-310 (IOS Press)
openalex publication_date 2002/12/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30
Traumatic brain injury (TBI) is frequently complicated by disinhibition and aggression. These often profound changes in personality, present obstacles to rehabilitative treatments and community reentry. Syndromal presentations may involve a loss of impulse control, spontaneous aggression, and dysphoric bipolar states. Common neuropathological findings of inferior frontal lobe dysfunction support both disinhibition and kindling models of TBI-induced aggression. Assessment of these highly disruptive symptoms requires detailed historical, clinical, and neuropsychological information to formulate appropriate strategies. Management of TBI-related aggression may involve pharmacological, environmental, and psychotherapeutic strategies that incorporate caregiver training and support.