2020/03/13 by Maria Ariadna Ochoa-Bernal, Asgerally T. Fazleabas · 1 citation
Immunology and Microbiology · Medicine · #Anatomy #Bioinformatics #Biology #Cell biology #Decidua #Decidualization #Embryo #Endometriosis Research and Treatment #Fetus #Genetics #Gynecological conditions and treatments #Human reproduction #Implantation failure #Infertility #Placenta #Pregnancy #Reproductive System and Pregnancy
paper · pdf · doi:10.3390/ijms21061973
openalex publication_date 2020/03/13 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06
Reproduction is a fundamental process for the preservation of the human species. This process requires a sequence of orchestrated events that are necessary for a successful pregnancy. Two of the most critical steps in the establishment of human pregnancy are implantation and decidualization, which are required for maternal interactions with the developing embryo. This review primarily highlights the physiological aspects of these two events and the adverse pregnancy outcomes from defective implantation and decidualization. The focus of this review is to provide a general concept of the mechanisms involved during the window of implantation, description of components involved in the process and possible pathologies that could disrupt the embryo implantation and decidualization and specifically as it applies to women and non-human primates.