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Lateral depletion effect on two-dimensional ordering of bacteriorhodopsins in a lipid bilayer: A theoretical study based on a binary hard-disk model

2020/11/12 by Keiju Suda, Ayumi Suematsu, Ryo Akiyama
Biochemistry, Genetics and Molecular Biology · Chemistry · Mathematics · Neuroscience · Physics and Astronomy · #Arithmetic #Bilayer #Binary number #Chemistry #Condensed matter physics #Lipid Membrane Structure and Behavior #Materials science #Mathematics #Membrane #Photoreceptor and optogenetics research #Physics #Spectroscopy and Quantum Chemical Studies #Statistical physics #acm:82B05 #acm:82B26 #cond-mat.soft #msc:82B05 #msc:82B26 #physics.chem-ph

paper · pdf · doi:10.1063/5.0044399

12 pages, 4 figures

arxiv created 2020/11/12 · openalex publication_date 2021/05/25 · arxiv updated 2021/06/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06

Abstract

The 2D ordering of bacteriorhodopsins in a lipid bilayer was studied using a binary hard-disk model. The phase diagrams were calculated taking into account the lateral depletion effects. The critical concentrations of the protein ordering for monomers and trimers were obtained from the phase diagrams. The critical concentration ratio agreed well with the experiment when the repulsive core interaction between the depletants, namely, lipids, was taken into account. The results suggest that the depletion effect plays an important role in the association behaviors of transmembrane proteins.

Citations