Resolving Intralocus Sexual Conflict: Genetic Mechanisms and Time Frame

2010/03/01 by Alexander Stewart, A. D. Stewart, A. Pischedda +3 · 105 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Allele #Animal Behavior and Reproduction #Biology #Computational biology #Evolutionary biology #Gene #Genetic Fitness #Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities #Genetic correlation #Genetic variation #Genetics #Phenotype #Sexual Differentiation and Disorders #Sexual conflict #Sexual dimorphism #Sexual selection #Trait #Zoology

paper · pdf · doi:10.1093/jhered/esq011

published in Journal of Heredity 101(Supplement 1), S94-S99 (Oxford University Press)

openalex publication_date 2010/03/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05

Abstract

Intralocus sexual conflict occurs due to the expression of sexually antagonistic alleles: those that increase fitness when expressed in one sex but decrease fitness when expressed in the other sex. This genetic conflict is expected whenever the sexes are selected toward differing phenotypic optima for a trait that has a positive genetic correlation between the sexes. Here we synthesize recent developments in the areas of genomics, microarray analysis, and developmental and molecular genetics to establish feasible mechanisms by which the intersexual genetic correlation can be reduced, as well as the time course over which conflict resolution is expected to evolve.

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