2023/03/01 by Sadhana Ravikumar, Ravikumar, Sadhana, Ranjit Ittyerah +61
Computer Science · Medicine · #Advanced MRI Techniques and Applications #Advanced Neuroimaging Techniques and Applications #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Medical Image Segmentation Techniques #electronic engineering #information engineering
paper · pdf · doi:10.48550/arxiv.2303.00795
openalex publication_date 2023/03/01 · openalex created_date 2023/03/05 · openalex updated_date 2026/08/01
When developing tools for automated cortical segmentation, the ability to produce topologically correct segmentations is important in order to compute geometrically valid morphometry measures. In practice, accurate cortical segmentation is challenged by image artifacts and the highly convoluted anatomy of the cortex itself. To address this, we propose a novel deep learning-based cortical segmentation method in which prior knowledge about the geometry of the cortex is incorporated into the network during the training process. We design a loss function which uses the theory of Laplace's equation applied to the cortex to locally penalize unresolved boundaries between tightly folded sulci. Using an ex vivo MRI dataset of human medial temporal lobe specimens, we demonstrate that our approach outperforms baseline segmentation networks, both quantitatively and qualitatively.