2022/11/23 by İlke Karayel-Hacıoğlu, Ilke Karayel-Hacioglu, Mehmet Özkan Timurkan +9 · 6 citations
Agricultural and Biological Sciences · Medicine · #Animal Virus Infections Studies #Biology #Congenital Anomalies and Fetal Surgery #Context (archaeology) #Gene #Genetic diversity #Genetics #Genome #Genotype #Group A #Medicine #Rotavirus #Strain (injury) #Veterinary medicine #Viral gastroenteritis research and epidemiology #Virology #Virus
paper · doi:10.1099/jgv.0.001808
published in Journal of General Virology 103(11) (Microbiology Society)
openalex publication_date 2022/11/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/25
Group A rotaviruses (RVAs) are a major cause of severe enteritis in humans and animals. RVAs have been identified in several animal species and their genetic diversity, the segmented nature of their RNA genome and the ability to spill over from one species to another can generate new RVA strains. In this study, we investigated the genome constellations of an unusual, rare, bovine RVA strain, G15P[21], identified from a farm with neonatal diarrhoea of calves in 2006. In parallel, the genome constellations of other RVA strains with different G/P types identified from the same farm in the same time span (2006-2008) were analysed. The genome constellation of strain K53 was G15-P[21]-I2-R2-C2-M2-A13-N2-T9-E2-H3 and was similar, overall, to that of the other bovine RVA strains (G6/10-P[11]-I2-R2-C2-M2-A13-N2-T6-E2-H3) with the exception of the NSP3 segment (T9 vs T6). This study describes RVA genomes with different genotype combinations isolated at a farm and also contributes to the understanding of the diversity and evaluation of rotavirus in a global context.