Non-permissiveness of synovial membrane cells to human parvovirus B19 in vitro

1992/06/01 by N. P. H. Miki, N.P.H. Miki, J. K. Chantler · 2 citations
Medicine · #Parvovirus B19 Infection Studies #Dermatological and COVID-19 studies

paper · doi:10.1099/0022-1317-73-6-1559

Abstract

The ability of cultured human synovial cells derived from synovial membrane and cartilage to support the replication of human parvovirus B19 was assessed. No viral DNA synthesis nor viral antigens were detected suggesting that B19 virus is not capable of replicating in synovial cells. The significance of this finding in relationship to the pathogenesis of parvovirus arthritis is discussed.

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• Advances in the biology, diagnosis and host–pathogen interactions of parvovirus B19
• Parvovirus B19 in Rheumatic Diseases. [europepmc]

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