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Attempt to fulfil Koch's postulates for pyloric Campylobacter

1985/04/01 by Barry J. Marshall, John A. Armstrong, David B. McGechie +1 · 2 citations
Medicine · #Helicobacter pylori-related gastroenterology studies #Viral gastroenteritis research and epidemiology #Intestinal and Peritoneal Adhesions #Campylobacter #Gastritis #Ingestion #Medicine #Peptic ulcer #Gastroenterology #Chronic gastritis #Gastric mucosa #Internal medicine #Stomach #Bacteria #Biology

paper · doi:10.5694/j.1326-5377.1985.tb113443.x

openalex publication_date 1985/04/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11

Abstract

A volunteer with histologically normal gastric mucosa received pyloric campylobacter by mouth. A mild illness developed, which lasted 14 days. Histologically proven gastritis was present on the tenth day after the ingestion of bacteria, but this had largely resolved by the fourteenth day. The syndrome of acute pyloric campylobacter gastritis is described. It is proposed that this disorder may progress to a chronic infection which predisposes to peptic ulceration.

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