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Molecular modelling with spherical Gaussians

1970/09/01 by B. Ford, Brian Ford, G. G. Hall +2
Chemistry · Computer Science · #Chemical Thermodynamics and Molecular Structure #Free Radicals and Antioxidants #Computational Drug Discovery Methods

paper · doi:10.1002/qua.560040508

Abstract

Abstract A mathematical model of a molecule is proposed. The electronic structure is described using a molecular orbital wave function constructed from a small number of spherical Gaussians with optimized parameters. The models exhibit the desirable properties of numerical stability, objectivity and transferability. Results are given for CH 4 , C 2 H 6 , cyclo‐propane, H 2 O, CH 2 O and C 2 H 4 . They can be given a chemical interpretation in terms of chemical bonds, lone pairs and atomic cusps.

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